anti-Cytochrome B-245, alpha Polypeptide (CYBA) Antikörper

Bezeichnung:: anti-Cytochrome B-245, alpha Polypeptide Antikörper (CYBA)

Auf www.antikoerper-online.de finden Sie aktuell 57 Cytochrome B-245, alpha Polypeptide (CYBA) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Cytochrome B-245, alpha Polypeptide Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 70 Cytochrome B-245, alpha Polypeptide Produkte verfügbar.

Synonyme:: b558, CYBA, MGC80750, nmf333, P22-PHOX, p22phox, zgc:66077

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	CYBA	1535	P13498
	CYBA	13057	Q61462
	CYBA	79129	Q62737
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Cytochrome B-245, alpha Polypeptide Antikörper

Human Polyclonal CYBA Primary Antibody für IHC (fro), IF (p) - ABIN750538 : Walton, Shin, Tajinda, Heusner, Kogan, Miyake, Chen, Tamura, Matsumoto: Adult neurogenesis transiently generates oxidative stress. in PLoS ONE 2012 (PubMed)
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Human Monoclonal CYBA Primary Antibody für WB - ABIN1042639 : Taylor, Jesaitis: Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics. in Methods in molecular biology (Clifton, N.J.) 2008 (PubMed)
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Human Monoclonal CYBA Primary Antibody für IHC (fro), FACS - ABIN1042638 : Taylor, Burritt, Baniulis, Foubert, Lord, Dinauer, Parkos, Jesaitis: Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
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Weitere Antikörper gegen Cytochrome B-245, alpha Polypeptide Interaktionspartner

Human Cytochrome B-245, alpha Polypeptide (CYBA) Interaktionspartner

The TT genotype of rs4673 in the CYBA gene was associated with Diabetic Peripheral Neuropathy in Type 1 Diabetes patients (OR 4.997, 95% CI 1.403-19.083, p = 0.016).
Three new mutations of CYBA gene in four of 22 Iranian patients with autosomal recessive-Chronic granulomatous disease were found.
Data indicate an association between the GA genotype of single nucleotide polymorphism rs3794624 in cytochrome b (zeige MT-CYB Antikörper)-245, alpha polypeptide (zeige ITGAE Antikörper) (CYBA) with decreased tuberculosis susceptibility in two Chinese populations.
in patients with very severe chronic obstructive pulmonary disease the NADPH oxidase subunit p22phox is significantly reduced as compared to controls; p22phox is a key player in COPD and in hypoxic pulmonary vascular remodelling
data demonstrated that rs4673 transition in p22phox gene may be involved in susceptibility to coronary artery disease and could be applied as a potential biomarker for this disease.
Data suggest that an SNP in NADPH oxidase (zeige NOX1 Antikörper) p22phox (C242T) is associated with nephropathy leading to macroalbuminuria in diabetic patients; this report is a meta-analysis of case-control genetic association studies. [META-ANALYSIS]
Together with the increased p22phox expression in lungs of asthmatic patients, findings demonstrate a crucial role of p22phox-dependent NADPH oxidase (zeige NOX1 Antikörper) for the development of mucus hypersecretion and airway hyperresponsiveness in house dust mite-induced model of asthma.
Results showed that variations of the C242T polymorphism of the CYBA gene altered the risk of developing neonatal respiratory distress syndrome, retinopathy of prematurity, and bronchopulmonary dysplasia.
In a family study of a patient with chronic granulomatous disease, the mutation in the CYBB (zeige CYBB Antikörper) gene was confirmed to be pathogenic, and the three variants in the CYBA gene were benign.
We demonstrated that rapid deletion of p22phox is possible and that the activity of Nox1 (zeige NOX1 Antikörper) and Nox4 (zeige NOX4 Antikörper) but not Nox5 (zeige NOX5 Antikörper) exclusively depends on p22phox.

Mouse (Murine) Cytochrome B-245, alpha Polypeptide (CYBA) Interaktionspartner

In p22phox(-/-) mice, hypoxic pulmonary vasoconstriction (HPV) was significantly impaired. In the chronic hypoxic setting, lack of p22phox was associated with improved right ventricular function and decreased pulmonary vascular remodelling.
Together with the increased p22phox expression in lungs of asthmatic patients, findings demonstrate a crucial role of p22phox-dependent NADPH oxidase (zeige NOX1 Antikörper) for the development of mucus hypersecretion and airway hyperresponsiveness in house dust mite-induced model of asthma.
Identification of a PPAR-gamma (zeige PPARG Antikörper) --> NF-kappaB (zeige NFKB1 Antikörper) --> p22phox neuroprotective signaling cascade opens a new avenue for protecting the brain against ischemic insult.
Knockout of the cytochrome P450 reductase by CRISPR/Cas9 technology (POR(-/-)) in HEK293 cells overexpressing Nox4 or Nox5 did not interfere with ROS production in intact cells. However, POR(-/-) abolished the signal in NADPH-stimulated assays using membrane fractions from the very same cells. Moreover, membranes of rat smooth muscle cells treated with angiotensin II showed an increased NADPH-dependent signal with lucigen
p22phox mRNA expression was increased in diet-induced obese (DIO) mice.
The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (zeige NOX1 Antikörper)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.
Vascular hnRNP-C expression is regulated by ROS (zeige ROS1 Antikörper) derived from NADPH (zeige FDXR Antikörper) oxidases and that the effects of NADPH oxidase (zeige NOX1 Antikörper) on vascular activation are mediated in part by protein kinase (zeige CDK7 Antikörper) CK1alpha (zeige CSNK1A1 Antikörper).
Enhanced p22(phox) expression causes vascular dysfunction through ERK1/2 and p38-mitogen-activated protein kinase (zeige MAPK14 Antikörper)-dependent mechanisms in male type 2 diabetic mice.
The first quantitative characterization of the interactions made between the cytosolic regulators NOXO1 (zeige NOXO1 Antikörper) and NOXA1 (zeige NOXA1 Antikörper) and membrane-bound p22(phox), is presented.
renal expression of Nox-2 (zeige CYBB Antikörper), p22(phox), and p47(phox), components of NADPH oxidase (zeige NOX1 Antikörper), are upregulated in GSD-Ia mice compared with controls

Pig (Porcine) Cytochrome B-245, alpha Polypeptide (CYBA) Interaktionspartner

Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis.
CRP (zeige CRP Antikörper) inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H (zeige NQO1 Antikörper) oxidase via p38 (zeige MAPK14 Antikörper) kinase activation
Reactive oxygen species generated by NADPH oxidase (zeige NOX1 Antikörper) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

Rabbit Cytochrome B-245, alpha Polypeptide (CYBA) Interaktionspartner

Angiotensin II inhibits the Na+/K+ pump via protein kinase c epsilon (zeige PRKCE Antikörper)-dependent activation of NADPH oxidase (zeige NOX1 Antikörper) subunits.

Cytochrome B-245, alpha Polypeptide (CYBA) Antigen-Profil

Beschreibung des Gens

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

Alternative names and synonyms associated with Cytochrome B-245, alpha Polypeptide (CYBA)

cytochrome b-245, alpha polypeptide (cyba) Antikörper
cytochrome b-245 alpha polypeptide L homeolog (cyba.L) Antikörper
cytochrome b-245, alpha polypeptide (CYBA) Antikörper
cytochrome b-245 alpha polypeptide (cyba) Antikörper
cytochrome b-245 light chain-like (LOC101328418) Antikörper
cytochrome b-245 alpha chain (CYBA) Antikörper
cytochrome b-245, alpha polypeptide (Cyba) Antikörper
cytochrome b-245 alpha chain (Cyba) Antikörper
p22-phox (CYBA) Antikörper

b558 Antikörper
CYBA Antikörper
MGC80750 Antikörper
nmf333 Antikörper
P22-PHOX Antikörper
p22phox Antikörper
zgc:66077 Antikörper

Bezeichner auf Proteinebene für CYBA

, , , , , , , , , , , , , , , , , , , , , , , P22phox cytochrome b-245, alpha polypeptide predicted cytochrome b-245, alpha polypeptide Cytochrome b(558) alpha chain Cytochrome b558 subunit alpha Neutrophil cytochrome b 22 kDa polypeptide Superoxide-generating NADPH oxidase light chain subunit cytochrome b-245 light chain flavocytochrome b558 (p22phox) p22 phagocyte B-cytochrome cytochrome b light chain cytochrome b(558) alpha chain cytochrome b(558) alpha-subunit cytochrome b, alpha polypeptide cytochrome b558 subunit alpha flavocytochrome b-558 alpha polypeptide neutrophil cytochrome b 22 kDa polypeptide p22phox superoxide-generating NADPH oxidase light chain subunit cytochrome beta-558 p22 phox p22-phox cytochrome b558 alpha-subunit NADPH oxidase light chain subunit

GENE ID	SPEZIES
393551	Danio rerio
446853	Xenopus laevis
489664	Canis lupus familiaris
549234	Xenopus (Silurana) tropicalis
100135693	Ovis aries
101328418	Tursiops truncatus
1535	Homo sapiens
13057	Mus musculus
79129	Rattus norvegicus
281111	Bos taurus
397507	Sus scrofa
100008800	Oryctolagus cuniculus

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