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muscle-specific (zeige EIF3K Proteine) expression of myogenin in zebrafish embryos is controlled by multiple regulatory elements in the promoter
The results show that myogenin gene expression is more sensitive to nutrient conditions of fish than traditional indicators such as the RNA/DNA ratio.
myog cannot rescue myogenesis in the myod (zeige MYOD1 Proteine)/myf5 (zeige MYF5 Proteine) double morphant
Data show that MyoD (zeige MYOD1 Proteine) and myogenin associate with distinct chromatin states.
The study demonstrates an essential role of Setd2 in myoblast proliferation and differentiation, and uncovers Setd2-mediated molecular mechanism through regulating MyoG and p21.
Overexpression and knockdown of TLP revealed that the levels of muscle-specific myosin heavy chain and the myogenic transcription factor myogenin are downregulated by TLP. The proximal AT-rich sequence of the myogenin promoter is responsible for TLP-mediated transcriptional repression.
This suggests that 4.1R (zeige EPB41 Proteine) may influence myogenesis by preventing VHL (zeige VHL Proteine)-mediated myogenin degradation.
Findings indicate a interplay between A-kinase anchoring protein (zeige MYRIP Proteine) 6 (AKAP6) and myogenin.
In summary, our results implicate that metastatic properties of some RMS subtypes might be linked to c-Myb (zeige MYB Proteine) function.
The Myf5 (zeige MYF5 Proteine)- and Myogenin-deficient mice showed a partial or complete, respectively, loss of TMC (zeige STT3A Proteine) in an otherwise regularly structured thymus.
Dach2 (zeige DACH2 Proteine) and Hdac9 (zeige HDAC9 Proteine) mediate the effects of muscle activity on muscle reinnervation; Myog and Gdf5 (zeige GDF5 Proteine) appear to stimulate muscle reinnervation through parallel pathways
Combining chemical with mechanical factor increases expression and there was no significant difference in MyoG expression of ESCs (zeige NR2E3 Proteine)- and MSCs-chemical + mechanical groups
TWIST reverses muscle cell differentiation through promoter binding and down-regulation of myogenin.
Findings indicate a interplay between A-kinase anchoring protein 6 (AKAP6) and myogenin.
results indicate that myogenin is a positive regulator in transcriptional regulation of MEGF10 (zeige MEGF10 Proteine) in skeletal muscle
Sustained GSK3beta activity represses a critical regulatory step in the myogenic cascade, contributing to the undifferentiated, proliferative phenotype in alveolar rhabdomyosarcoma.
Our study illustrates that focal myogenin immunoreactivity occurs uncommonly in fibroepithelial polyps of the lower female genital tract.
Data indicate that muscle MYOG mRNA expression doubled, whereas MSTN (zeige MSTN Proteine) protein expression decreased following immobilization.
SREBP-1 (zeige SREBF1 Proteine) regulate muscle protein synthesis through the downregulation of the expression of MYOD1 (zeige MYOD1 Proteine), MYOG and MEF2C (zeige MEF2C Proteine) factors.
the FACT complex promotes myogenin-dependent transcription
Human muscle samples were analysed at different time-points post-denervation to evaluate changes in myogenin expression and their relationship with skeletal muscle atrophy.
After 2 years of denervation, expression of myogenin protein in myonuclei was decreased, but after 3 years of denervation, no expression of myogenin protein in myonuclei was found in denervated posterior cricoarytenoid muscles.
The physical interaction of CARM1 (zeige CARM1 Proteine) and PCAF (zeige KAT2B Proteine) is likely pivotal for the activation of PCAF (zeige KAT2B Proteine) in the downstream of CARM1 (zeige CARM1 Proteine) pathway for inducing myogenin under Tetradecanoylphorbol Acetate -induced differentiation.
the MyoG gene is very conservative and there are very few mutation sites between different breeds
mutation in exon 1 of the MYOG gene had no statistically significant association with carcass quality traits
Significant differences were found in the birth weight and the backfat thickness among the different MyoG genotypes
Relative MYOD1 (zeige MYOD1 Proteine) expression was not different, but MYOG expression was higher in the (ligated-tube)crowded group embryos.
EGR1 (zeige EGR1 Proteine) can promote skeletal muscle satellite cell differentiation through positive regulation of MyoG gene expression.
data suggested that miR (zeige MYLIP Proteine)-2400 could promote MDSCs proliferation through targeting MYOG
the MyoG SNP has potential as a genetic marker for economically relevant body measurement traits in native Chinese cattle breeds.
Studied and compared mRNA levels of myostatin (MSTN (zeige MSTN Proteine)), myogenin (MyoG), and myosin heavy chain (MyHC) in skeletal muscles of two rabbit breeds with different body sizes and growth rates.
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle.
, myogenin (myogenic factor 4)
, MYOD1-related protein
, class C basic helix-loop-helix protein 3
, myogenic factor 4
, myogenic factor