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Mouse (Murine) Polyclonal APOA1 Primary Antibody für ICC, IF - ABIN153495
Duong, Collins, Nickel, Lund-Katz, Rothblat, Phillips: Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I. in Journal of lipid research 2006
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Human Polyclonal APOA1 Primary Antibody für IHC (p), IP - ABIN152915
Vedhachalam, Duong, Nickel, Nguyen, Dhanasekaran, Saito, Rothblat, Lund-Katz, Phillips: Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles. in The Journal of biological chemistry 2007
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Human Polyclonal APOA1 Primary Antibody für IF (p), IHC (p) - ABIN728968
Liu, Zhao, Lu, Fan, Wang: Proteomic study on usnic-acid-induced hepatotoxicity in rats. in Journal of agricultural and food chemistry 2012
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Human Monoclonal APOA1 Primary Antibody für ELISA, WB - ABIN1724693
Brown, Rea, Hamon, Hixson, Boerwinkle, Clark, Sing: The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability. in Journal of molecular medicine (Berlin, Germany) 2006
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Mouse (Murine) Monoclonal APOA1 Primary Antibody für WB - ABIN968823
Cuthbert, Wang, Zhang, Tam: Regulation of human apolipoprotein A-I gene expression by gramoxone. in The Journal of biological chemistry 1997
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Rat (Rattus) Monoclonal APOA1 Primary Antibody für WB - ABIN968824
Poncin, Martial, Gielen: Cloning and structure analysis of the rat apolipoprotein A-I cDNA. in European journal of biochemistry / FEBS 1984
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Human Polyclonal APOA1 Primary Antibody für EIA, IHC (fro) - ABIN116540
Bernthaler, Epping, Schmitz, Deplazes, Brehm: Molecular characterization of EmABP, an apolipoprotein A-I binding protein secreted by the Echinococcus multilocularis metacestode. in Infection and immunity 2009
Human Polyclonal APOA1 Primary Antibody für ELISA, WB - ABIN2477464
Thomson, Molina-Portela, Mott, Carrington, Raper: Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes. in Proceedings of the National Academy of Sciences of the United States of America 2009
Human Polyclonal APOA1 Primary Antibody für ELISA, WB - ABIN4281164
Gursky, Mei, Atkinson: The crystal structure of the C-terminal truncated apolipoprotein A-I sheds new light on amyloid formation by the N-terminal fragment. in Biochemistry 2012
Human Monoclonal APOA1 Primary Antibody für IHC (fro), ELISA - ABIN2477462
Richter, Buck: Family practice residents and the elderly: fostering positive attitudes. in Family medicine 1990
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Smaller apolipoprotein(a) isoform size and increased lipoprotein(a) concentration are independent and causal risk factors for coronary heart disease.
Serum ApoA-I level was negatively correlated with the formation of vocal fold polyps, suggesting ApoA-I may reduce the risk of vocal fold polyps.
data indicate that low apoA1 levels are an independent predictor of the poor clinical outcomes in invasive ductal carcinoma patients.
Data suggest that Apolipoprotein A1 (ApoA-1) might be a promising therapeutic target to reduce recurrence and metastasis for hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) patients after resection.
The generated structures provide evidence for the discoidal, antiparallel arrangement of apoA-I in nascent HDL (zeige HSD11B1 Antikörper), and propose two preferred conformations of the flexible N-termini
identified that apolipoprotein-A1 and haptoglobin (zeige HP Antikörper) had significant predictive values for the prediction of recovery at 12 weeks in DILI, enabling the construction of a new prognostic panel, the DILI-ActiTest, which needs to be independently validated
ApoA1 is associated with neurite outgrowth after mechanical injury by mediating polymerisation of actin and restricting inflammatory responses after injury which are deleterious to healing.
A retractable lid in lecithin:cholesterol acyltransferase provides a structural mechanism for activation by apolipoprotein A-I
Lower ApoA1 improves the risk prediction of new type 2 diabetes
Following ETC-216 administration to normal human volunteers, an initial dose-dependent HDL (zeige HSD11B1 Antikörper)-C elevation was observed. Thereafter, subjects transiently acquired a lipoprotein profile similar to that of AIM carriers, including reduced HDL (zeige HSD11B1 Antikörper)-C and mild hypertriglyceridemia.
These results suggested that apoA-I overexpression could reduce steatosis by decreasing lipid levels and by suppressing endoplasmic reticulum stress and lipogenesis in hepatocytes. ApoA-I expression could significantly reduce hepatic ER stress and lipogenesis in hepatocytes.
ABCA1 (zeige ABCA1 Antikörper)-derived nascent high-density lipoprotein-apolipoprotein AI and lipids metabolically segregate.
apoA-I/ABCA1 (zeige ABCA1 Antikörper)-mediated cholesterol efflux without STAT3 (zeige STAT3 Antikörper) activation can reduce proinflammatory cytokine expression in macrophages.
a novel protective role for ApoA-I in colitis and CAC (zeige SLC25A20 Antikörper)
Our results assign a novel role for 4F(apoA-I mimetic peptide ) as a modulator of the TICE pathway and suggest that the anti-inflammatory functions of 4F may be a partial consequence of the codependent intestinal transport of both 4F and cholesterol.
Preincubation of endothelial cells with apoA-I protected against the TNF-alpha (zeige TNF Antikörper)-induced inhibition of HTR (zeige F2R Antikörper)-8/SVneo (trophoblast) cell integration into endothelial (UtMVEC) networks. These data suggest that a healthy lipid profile may affect pregnancy outcomes by priming endothelial cells in preparation for trophoblast invasion.
Reductions in Dio1 (zeige DIO1 Antikörper) expression reduce the expression of ApoA-I in a 3,5,3'-triiodothyronine-/thyroid hormone (zeige PTH Antikörper) response element-independent manner.
apoA-1 deficiency generates changes in the bone cell precursor population that increase adipoblast, and decrease osteoblast production resulting in reduced bone mass and impaired bone quality
This study suggests that enhancement of macrophage cholesterol metabolism by PPARgammais not contributed by activating ABCA1 (zeige ABCA1 Antikörper) expression and ABCA1 (zeige ABCA1 Antikörper)-mediated cholesterol efflux to apoAI, which is not involved by CD36 (zeige CD36 Antikörper) expression either.
Mass spectrometry analysis of peptides derived from chemically crosslinked HDL (zeige HSD11B1 Antikörper)-SAA (zeige SAA1 Antikörper) particles detected multiple crosslinks between apoA1 and SAA (zeige SAA1 Antikörper), indicating close proximity (within 25 A) of these two proteins on the HDL (zeige HSD11B1 Antikörper) surface, providing a molecular and structural mechanism for the simultaneous binding of heparin to apoA1 and SAA (zeige SAA1 Antikörper).
insulin (zeige INS Antikörper) secretion and tissue rejuvenation activities of WT-reconstituted high-density lipoproteins were nearly depleted by fructosylation, but V156K-rHDL did not lose its beneficial activity.
The NABB system using engineered zebrafish apo A-I is a native-like membrane mimetic system for G-protein-coupled receptors.
Binding of apoA-I to ectopic F(0)F(1) ATPase (zeige ATP5E Antikörper) triggers the generation of ADP, which via activation of the purinergic receptor P2Y (zeige P2RY1 Antikörper)(12) stimulates the uptake and transport of HDL (zeige HSD11B1 Antikörper) and initially lipid-free apoA-I by endothelial cells.
the model of a two-step process for the transendothelial transport of apoA-I in which apoA-I is initially lipidated by ABCA1 (zeige ABCA1 Antikörper) and then further processed by ABCA1 (zeige ABCA1 Antikörper)-independent mechanisms.
This study showed that apoA-I exerted protective effects against fatty liver disease in rabbits induced by a high-fat diet, possibly through its antioxidant actions.
The molar ratio ApoE (zeige APOE Antikörper)/ApoA-I is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs.
Alterations in the Apo A (zeige APOA Antikörper)-I pattern is a good indicator of the presence and severity of infectious diseases in the pig.Lower overall amounts of Apo A (zeige APOA Antikörper)-I were observed in Salmonella typhimurium and Escherichia coli infections.
down-regulation of apolipoprotein A-I and A-IV messages in the liver may be mediated by interleukin 6 (zeige IL6 Antikörper) and tumor necrosis factor-alpha (zeige TNF Antikörper)
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
, apolipoprotein A1
, apolipoprotein A-1
, preproapolipoprotein A-I
, apolipoprotein A-I
, apolipoprotein A-I preproprotein
, Apolipoprotein A1
, apolipoprotein A-I-like
, Apolipoprotein A-I