Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) CD226 Antikörper:
anti-Human CD226 Antikörper:
anti-Rat (Rattus) CD226 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Monoclonal CD226 Primary Antibody für FACS - ABIN4896040
Brunetta, Fogli, Varchetta, Bozzo, Hudspeth, Marcenaro, Moretta, Mavilio: The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia. in Blood 2009
Show all 2 Pubmed References
Human Monoclonal CD226 Primary Antibody für Func, FACS - ABIN1177314
Shibuya, Campbell, Hannum, Yssel, Franz-Bacon, McClanahan, Kitamura, Nicholl, Sutherland, Lanier, Phillips: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. in Immunity 1996
Human Monoclonal CD226 Primary Antibody für FACS - ABIN2479330
Fretz, Stark, Metz, Elizondo, Weissleder, Shen, Wittenberg, Simeone, Ferrucci: Detection of hepatic metastases: comparison of contrast-enhanced CT, unenhanced MR imaging, and iron oxide-enhanced MR imaging. in AJR. American journal of roentgenology 1990
Show all 4 Pubmed References
Human Monoclonal CD226 Primary Antibody für FACS, IP - ABIN2479326
Shibuya, Lanier, Phillips: Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. in Journal of immunology (Baltimore, Md. : 1950) 1998
Show all 4 Pubmed References
Human Monoclonal CD226 Primary Antibody für Func, FACS - ABIN2479328
Kojima, Kanada, Shimizu, Kasama, Shibuya, Nakauchi, Nagasawa, Shibuya: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. in The Journal of biological chemistry 2003
Show all 4 Pubmed References
Human Monoclonal CD226 Primary Antibody für FACS - ABIN4896039
Liu, Qian, Chen, Xu, Gao, Zhang, Zhang, Qi, Gao, Yan: Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226. in Journal of immunology (Baltimore, Md. : 1950) 2012
Human Monoclonal CD226 Primary Antibody für CyTOF, FACS - ABIN4899393
Magnani, Alberigo, Bacchetta, Serafini, Andreani, Roncarolo, Gregori: Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells. in European journal of immunology 2011
Results indicate that low-grade inflammation coupled with elevated blood glucose increases CD226 expression, resulting in decreased endothelial cell glucose uptake in T2DM.
Data show that the severity experimental autoimmune encephalomyelitis (EAE) were reduced and the serum IL-10 (zeige IL10 Antikörper) expression levels were increased in CD226 knockout mice than that in control mice when both received EAE induction.
Blocking CD226 inhibited NK cell-mediated cytotoxicity of the GM-CSF (zeige CSF2 Antikörper)-stimulated Flt3 ligand (zeige FLT3LG Antikörper) conventional dendritic cells. The CD226(+)NKG2A (zeige KLRC1 Antikörper)(-) subset of NK cells was better at targeting GM-CSF (zeige CSF2 Antikörper)-stimulated Flt3 ligand (zeige FLT3LG Antikörper) conventional dendritic cells. CD155 (zeige PVR Antikörper), a known ligand for CD226, could also act as an inhibitor of NK cell-mediated lysis, as dendritic cells lacking CD155 (zeige PVR Antikörper) were more sensitive to NK cell-mediated lysis.
inflammatory monocytes, together with NK cells, are essential in the early control of CMV through the DNAM-1-PVR (zeige PVRL2 Antikörper) pathway.
Data show that CD155 (zeige PVR Antikörper) protein/CD226 antigen mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia (zeige BCL11A Antikörper). To investigate the interaction between leukemic cells
absence of either CD155 (zeige PVR Antikörper) or CD226 in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells.
our results suggest a limited role for DNAM-1 in solid allograft rejection. Blocking DNAM-1 is not sufficient to prevent allograft rejection and might be relevant only in combination with additional inhibitors of costimulation.
we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (zeige NCAM1 Antikörper) on blood inflammatory monocytes.
Data indicate that DNAM-1 (CD226) signaling was required to enhance cytotoxicity.
Regulatory T cells derived (zeige CD4 Antikörper)from Cd226-deficient mice showed similarly reduced inhibitory activity, eventually resulting in an exacerbated disease course of experimental autoimmune encephalomyelitis.
Natural killer cells and cytotoxic T cells express both TIGIT (zeige TIGIT Antikörper) and DNAM-1 receptors, and in certain cases their effector functions are dictated by TIGIT (zeige TIGIT Antikörper) or DNAM-1 signaling. Agonist and antagonist antibodies targeting either TIGIT (zeige TIGIT Antikörper) or DNAM-1 present many therapeutic options for diseases spanning from cancer to auto-immunity. (Review)
Results show that CD226 expression was down-regulated in human hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) cells. MiR (zeige MLXIP Antikörper)-892a directly targeted CD226 promoting HCC (zeige FAM126A Antikörper) cells proliferation and invasion.
cumulative incidences of acute graft-versus-host disease in patients with high maximal serum levels of sDNAM-1 (>/=30 pM) in the 7 days before allogeneic hematopoietic stem cell transplantation were significantly higher than those in patients with low maximal serum levels of sDNAM-1 in the same period. Our data suggest sDNAM-1 is potentially a unique candidate as a predictive biomarker for the development of acute GVHD.
Our results support an important association of rs4810485 in CD40 (zeige CD40 Antikörper) gene and rs763361 in CD226 gene polymorphism, combined effect of rs4810485 and rs763361 with increased risk of systemic lupus erythematosus.
our results support and explain the mechanism behind the recently reported finding that in EOC, NK-cell recognition and killing of tumor cells was mainly dependent on DNAM-1 signaling while the contribution of the NKG2D (zeige KLRK1 Antikörper) receptor-ligand pathway was complementary and uncertain.
CD226 rs763361 polymorphism was significantly associated with susceptibility to T1D.
Age and CMV serostatus influence the expression of NKp30 (zeige NCR3 Antikörper), NKp46 (zeige NCR1 Antikörper) and DNAM-1 activating receptors on resting and IL-2 (zeige IL2 Antikörper) activated natural killer cells.
DNAM-1 ligands CD112 (zeige PVRL2 Antikörper) and CD155 (zeige PVR Antikörper) as well as the NKG2D (zeige KLRK1 Antikörper) ligands MICA (zeige MICA Antikörper) and MICB (zeige MICB Antikörper) were expressed on the hiPSC lines
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.
, CD226 molecule
, platelet and T cell activation antigen 1
, platelet and T-cell activation antigen 1
, DNAX accessory molecule 1
, DNAX accessory molecule-1
, T lineage-specific activation antigen 1 antigen
, adhesion glycoprotein