Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human GARP Antikörper:
anti-Rat (Rattus) GARP Antikörper:
anti-Mouse (Murine) GARP Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Here, we present the first case of RP45 caused by an unequivocal homozygous nonsense variant of CNGB1 identified by run of homozygosity (ROH) analysis.
Helios (zeige ZNFN1A2 Antikörper), and not FoxP3 (zeige FOXP3 Antikörper), is the marker of activated Tregs expressing GARP/LAP, and FoxP3 (zeige FOXP3 Antikörper)+Helios (zeige ZNFN1A2 Antikörper)+ Tregs have more suppressive characteristics, compared with FoxP3 (zeige FOXP3 Antikörper)+Helios (zeige ZNFN1A2 Antikörper)- Tregs.
GARP2 expression in cones can be detrimental to cones. RDS (zeige PRPH2 Antikörper)/GARP interactions remain under investigation but are critical for both OS structure and function.
Deletion of the cyclic nucleotide gated channel CNGB1 alters response waveform but leaves light adaptation intact in a transgenic model.
When expressed in a heterologous expression system the corresponding mutant full-length CNGB1a subunit was more susceptible to proteosomal degradation compared to the wild-type counterpart
we report targeting of cyclic nucleotide-gated channel(CNG (zeige CNGA1 Antikörper)) to rod outer segment required interaction with ankyrin-G (zeige ANK3 Antikörper); ankyrin-G (zeige ANK3 Antikörper) localized to rod outer segments, coimmunoprecipitated with CNG (zeige CNGA1 Antikörper) channel & bound to C-terminal domain of channel beta1 subunit
Three CNGA1 (zeige CNGA1 Antikörper) subunits and a single CNGB1 subunit form the rod cyclic nucleotide-gated ion channels.
Glutamic acid-rich proteins could provide the environment needed for protein interactions in the rim (zeige RBBP8 Antikörper) region of optic discs.
Results suggest a novel role for glutamic acid-rich protein-2 as a regulator of spontaneous activation of rod photoreceptor phosphodiesterase, allowing rods to operate at the single photon detection limit.
olfactory sensory neurons in NCKX4 (zeige Slc24a4 Antikörper)(-/-);CNGB1(DeltaCaM) mice displayed markedly reduced electro-olfactogram amplitude accompanied by alterations in other response attributes
Overexpression of rod photoreceptor glutamic acid rich protein 2 (GARP2) increases gain and slows recovery in mouse retina
Eliminating Cngb1 and reducing RDS (zeige PRPH2 Antikörper) leads to additive defects in RDS (zeige PRPH2 Antikörper) expression levels and rod electroretinogram (ERG (zeige ERG Antikörper)) function, (e.g., Cngb1-/-/rds (zeige PRPH2 Antikörper)+/- versus rds (zeige PRPH2 Antikörper)+/- or Cngb1-/-) but not to additive defects in rod ultrastructure.
Peripherin-2 (zeige PRPH2 Antikörper) links CNGB1 to the light-detector rhodopsin (zeige RHO Antikörper) in outer segments of rod photoreceptors.
These results confirm that rods are marginally functional in the absence of the beta-subunit (zeige POLG Antikörper) and in addition show that CFF (zeige HCFC1 Antikörper) (critical flicker frequency)may be a more sensitive measure of remaining functional cone vision
In Cngb1(-/-) x rd1 (zeige PDE6B Antikörper) double mutants, cGMP levels are high, but rod photoreceptor viability and outer segment morphology are improved.
Deletion of the cyclic nucleotide gated channel CNGB1 alters response waveform but leaves light adaptation intact.
Our results show that CNGB1 is a crucial determinant of native cyclic nucleotide-gated channel targeting.
The role of CNGB1 in the function of the olfactory bulb and nucleotide-gated ion channel function is reported.
Ca2 (zeige CA2 Antikörper)+/calmodulin-mediated CNG (zeige CNGA1 Antikörper) channel fast desensitization is less important in regulating the sensitivity to recurring stimulation than previously thought and instead functions primarily to terminate olfactory sensory neuron responses
Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.
CNG channel beta-1
, cyclic nucleotide-gated cation channel 4
, cyclic nucleotide-gated cation channel beta-1
, cyclic nucleotide-gated cation channel gamma
, cyclic nucleotide-gated cation channel modulatory subunit
, cyclic nucleotide-gated channel beta-1
, glutamic acid-rich protein
, glutamic-acid-rich protein
, cyclic nucleotide-gated channel beta subunit 1
, 240 kDa protein of rod photoreceptor CNG-channel
, CNG channel 4
, cDNA sequence BC016201
, hyperpolarization activated cyclic nucleotide-gated potassium channel 4
, cyclic nucleotide gated channel alpha 4
, cardiac hyperpolarization-activated current subunit 4
, cyclic nucleotide gated channel beta 1
, cyclic nucleotide gated channel alpha 3-like
, Cyclic nucleotide-gated cation channel alpha-4-like
, cyclic nucleotide-gated cation channel beta-1-like
, cyclic nucleotide-gated cation channel alpha-4-like