TMEM123 Proteine (TMEM123)

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

• transmembrane protein 123 (TMEM123)
• transmembrane protein 123 (Tmem123)
• transmembrane protein 123 L homeolog (tmem123.L)
• transmembrane protein 123 (tmem123)

• 2310075C12Rik Protein
• kct3 Protein
• porimin Protein
• pormin Protein
• RGD1305625 Protein

KCT-3 , keratinocytes associated transmembrane protein 3 , keratinocytes-associated transmembrane protein 3 , porimin , pro oncosis receptor inducing membrane injury , pro-oncosis receptor inducing membrane injury , serine/threonine-rich receptor , transmembrane protein 123