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Nek5 (zeige NEK6 Proteine) promotes myogenic differentiation through up-regulation of caspase-3 (zeige CASP3 Proteine) activity.
The hNek5 is mitochondrial localization and its role on cell death and cell respiration defects through COX11, MTX2 and BCLAF1.
Nek5 (zeige NEK6 Proteine) is required for the loss of centrosome linker proteins and enhanced microtubule nucleation that lead to timely centrosome separation and bipolar spindle formation in mitosis
Data demonstrated that NEK6 is required for the directional growth of roots and hypocotyls, petiole elongation, cell file formation, and trichome morphogenesis.
NEK6 regulates rosette growth and yield-related traits in Arabidopsis.
NEK6 homodimerizes and forms heterodimers with NEK4 and NEK5 (zeige NEK6 Proteine) to regulate cortical microtubule organization possibly through the phosphorylation of beta-tubulins.
interacts with ARIA and is involved in abscisic acid response during seed germination
ibo1-1 mutation, in which a conserved Glu residue in the activation loop is substituted by Arg, completely abolishes its kinase activity
Involved in epidermal-cell morphogenesis in hypocotyls and roots. May act on the microtubule function. May have a secondary role in trichome branching.
NIMA-related kinase 5
, never in mitosis A-related kinase 5
, nimA-related protein kinase 5
, serine/threonine-protein kinase Nek5
, NIMA (never in mitosis gene a)-related kinase 5