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anti-Mouse (Murine) CCR7 Antikörper:
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Human Monoclonal CCR7 Primary Antibody für CyTOF, FACS - ABIN4899110
Lee, Fertig, Jin, Sukumar, Pandey, Popel: Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. in Nature communications 2014
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Human Monoclonal CCR7 Primary Antibody für FACS - ABIN4895614
Santra, Tomaras, Warrier, Nicely, Liao, Pollara, Liu, Alam, Zhang, Cocklin, Shen, Duffy, Xia, Schutte, Pemble Iv, Dennison, Li, Chao, Vidnovic, Evans, Klein, Kumar, Robinson, Landucci, Forthal et al.: Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques. ... in PLoS pathogens 2015
Show all 34 Pubmed References
Human Monoclonal CCR7 Primary Antibody für FACS - ABIN4895619
Kaur, Sanford, Garry, Lang, Klumpp, Watanabe, Bronson, Lifson, Rosati, Pavlakis, Felber, Knipe, Desrosiers: Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus. in Virology 2006
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Human Polyclonal CCR7 Primary Antibody für ELISA, FACS - ABIN152135
Schweickart, Raport, Godiska, Byers, Eddy, Shows, Gray: Cloning of human and mouse EBI1, a lymphoid-specific G-protein-coupled receptor encoded on human chromosome 17q12-q21.2. in Genomics 1995
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Human Monoclonal CCR7 Primary Antibody für FACS - ABIN2689061
Kim, Pelus, White, Broxmeyer: Macrophage-inflammatory protein-3 beta/EBI1-ligand chemokine/CK beta-11, a CC chemokine, is a chemoattractant with a specificity for macrophage progenitors among myeloid progenitor cells. in Journal of immunology (Baltimore, Md. : 1950) 1998
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Human Monoclonal CCR7 Primary Antibody für FACS - ABIN2689059
Birkenbach, Josefsen, Yalamanchili, Lenoir, Kieff: Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. in Journal of virology 1993
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Human Monoclonal CCR7 Primary Antibody für FACS - ABIN2689060
Burgstahler, Kempkes, Steube, Lipp: Expression of the chemokine receptor BLR2/EBI1 is specifically transactivated by Epstein-Barr virus nuclear antigen 2. in Biochemical and biophysical research communications 1995
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Human Monoclonal CCR7 Primary Antibody für FACS - ABIN4895610
Iyer, Gangadhara, Victor, Gomez, Basu, Hong, Labranche, Montefiori, Villinger, Moss, Amara: Codelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques. in Journal of immunology (Baltimore, Md. : 1950) 2015
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Mouse (Murine) Monoclonal CCR7 Primary Antibody für CyTOF, FACS - ABIN4900691
Irino, Takeuchi, Matsuda, Saikawa, Kawakubo, Wada, Takahashi, Nakamura, Fukuda, Omori, Kitagawa: CC-Chemokine receptor CCR7: a key molecule for lymph node metastasis in esophageal squamous cell carcinoma. in BMC cancer 2014
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Human Polyclonal CCR7 Primary Antibody für FACS, IF (p) - ABIN674724
Ge, Li, Jiang, You, Liu, Zhong, Huang, Xing: Integration of nondegradable polystyrene and degradable gelatin in a core-sheath nanofibrous patch for pelvic reconstruction. in International journal of nanomedicine 2015
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Ccr7 functions during axis formation as a GPCR to inhibit beta-catenin (zeige CTNNB1 Antikörper), likely by promoting Ca(2 (zeige CA2 Antikörper)+) transients throughout the blastula.
Data report that CCR7 mediates CD11c (zeige ITGAX Antikörper)+ cell migration from the CNS parenchyma to the meningeal lymphoid vessels and eventually to the deep cervical lymph nodes during neuroinflammation. In the absence of CCR7, dendritic cells are retained in the CNS and exacerbate neuroinflammation.
Conditions for optimal dendritic cells guidance are perfectly provided by the CCL21 (zeige CCL21 Antikörper) gradients measured in vivo. Furthermore, CCR7 signal termination by the G-protein-coupled receptor kinase 6 (GRK6 (zeige GRK6 Antikörper)) is crucial for haptotactic but dispensable for chemotactic CCL21 (zeige CCL21 Antikörper) gradient sensing in vitro and confirm those observations in vivo.
CCR7 deficiency results in apoptosis of Sirpa (zeige SIRPA Antikörper)- dendritic cells, which is counterbalanced by expansion of immature Sirpa (zeige SIRPA Antikörper)+ dendritic cells that efficiently induce Treg generation.
These data show that CCR7-CCL19 (zeige CCL19 Antikörper)/CCL21 (zeige CCL21 Antikörper) axis facilitates retention CD4 (zeige CD4 Antikörper)(+) T lymphocytes at the site of collateral artery remodeling, which is essential for effective arteriogenesis.
Results demonstrated that the deletion of CCR7 significantly decreases levels of activated Notch1 (zeige NOTCH1 Antikörper), and provide evidence that crosstalk between CCR7 and Notch1 (zeige NOTCH1 Antikörper) promotes stemness in mammary cancer cells ultimately potentiating mammary tumor progression.
CCR7 deficiency lead to accumulation of CD8 (zeige CD8A Antikörper)+ adipose tissue leukocytes, which was further exacerbated by HFD feeding.
in the current study, we used interval mapping to validate a locus on Chr 15, named Ity8, linked to Salmonella resistance in AcB60 mice. Global gene expression analysis during infection identified AcB60-specific expression of genes involved in Ccr7 signaling, including downstream effector Mapk11 (mitogen-activated protein kinase 11 (zeige MAPK11 Antikörper)), located within the Ity8 interval, and representing a potential positional candidate gene
Taken together, these data suggest that CCR7 biases memory CD8 (zeige CD8A Antikörper) T cells toward IL-7 (zeige IL7 Antikörper)-dependent niches over IL-15 (zeige IL15 Antikörper)-dependent niches, which provides insight into the homeostatic regulation of different memory T-cell subsets.
Prominent mucosal immune responses in CCR7-deficient mice increased the efficiency of bacteria clearance from the FRT(female reproductive tract) while reducing tissue-associated inflammation and pathology; increased numbers of lymphocytes within the FRT result in pathogen clearance with reduced immune-mediated pathology
CCR7 is required to mount a robust immune response against enteropathogenic Y. pseudotuberculosis by promoting Th17-like responses in mesenteric lymph nodes.
High CCR7 expression is associated with urinary bladder cancer metastasis.
these data indicate CCL19 (zeige CCL19 Antikörper)/CCR7 contributes to proliferation and invasion of ESCs (zeige NR2E3 Antikörper), which are conducive to the pathogenesis of endometriosis through activating PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) pathway
The research findings demonstrate for the first time that the chemokines CCL19 (zeige CCL19 Antikörper), CCL21 (zeige CCL21 Antikörper) and CCR7 play important roles in bone destruction by increasing osteoclast migration and resorption activity, and that has been linked to rheumatoid arthritis pathogenesis.
CXCR4 (zeige CXCR4 Antikörper), CCR7, VEGF-C (zeige VEGFC Antikörper) and VEGF-D (zeige Figf Antikörper) expression might have synergistic effects on the lymph node metastasis in patients with cervical cancer.
the acute GvHD (aGvHD) patients received higher percentage of CD4 (zeige CD4 Antikörper)+CCR7+ T-cells in donor T-cells, whereas chronic GvHD (cGvHD) patients were transplanted with higher percentages of CD8 (zeige CD8A Antikörper)+CCR7+ T-cells. Functional experiments demonstrated that CCR7+ T-cells exhibited higher potential for activation than CCR7- T-cells did.
these results demonstrated that CCL21/CCR7 may activate EMT in lung cancer cells via the ERK1/2 signaling pathway.
CCL21 (zeige CCL21 Antikörper)/CCR7 interaction was shown to allow NK cell adhesion to endothelial cells (ECs) and its reduction by hypoxia.
Study shows that miR (zeige MLXIP Antikörper)-1275 can positively regulate CCR7 expression in squamous cell carcinoma of head and neck (SCCHN) with different mechanisms.
Study provide evidence that CCR7 mediates EMT (zeige ITK Antikörper) progress via AKT (zeige AKT1 Antikörper) pathway, which indicates that CCR7 has a key role in breast cancer progression.
Report an increased percentage of peripheral CCR7 T cells accompanied by endothelial dysfunction in patients with ankylosing spondylitis.
Fluorescent dye-labeled gammadelta T cells from afferent and efferent lymph lack CCR7 surface expression and display high levels of CD62L (zeige SELL Antikörper) compared with CD4 (zeige CD4 Antikörper) T cells, which do express CCR7.
CCR7 transcripts were minimally expressed in ex vivo and proliferating WC1(+)gammadelta T cells, a unique cell population with proinflammatory characteristics
the pattern of expression of CCR7 in different populations of porcine lymphocytes appears to be similar to that of human, highlighting the value of the pig as a useful animal model for biomedical studies.
Pre-translntation of sertli cell CCR7 significantly suppresses lymphocyte proliferation and prolongs allogeneic skin graft survival.
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
C-C chemokine receptor type 7
, CC chemokine receptor 7
, chemokine (C-C motif) receptor 7 a
, chemokine (C-C motif) receptor 7
, c-C chemokine receptor type 7-like
, C-C CKR-7
, EBV-induced G-protein coupled receptor 1
, MIP-3 beta receptor
, chemokine (C-C) receptor 7
, epstein-Barr virus-induced G-protein coupled receptor 1
, EBV-induced G protein-coupled receptor 1
, Epstein-Barr virus induced G-protein coupled receptor
, Epstein-Barr virus induced gene 1
, lymphocyte-specific G protein-coupled peptide receptor
, chemokine receptor 7