RENT2/UPF2 Produkte
(UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
Kategorien
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene\\\\; both variants encode the same protein. [provided by RefSeq, Jul 2008].
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Ausgewählte RENT2/UPF2 Kategorien
RENT2/UPF2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene RENT2/UPF2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN6149941
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (2)
Kat. Nr.
ABIN654649
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6570914
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene RENT2/UPF2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3095007
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2735035
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RENT2/UPF2 Produkten
: "Compound C inhibits nonsense-mediated RNA decay independently of AMPK." in: PLoS ONE, Vol. 13, Issue 10, pp. e0204978, (2019) (PubMed).: "Intracellular calcium regulates nonsense-mediated mRNA decay." in: Nature medicine, Vol. 20, Issue 8, pp. 961-6, (2014) (PubMed).
: "CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells." in: Nature structural & molecular biology, Vol. 12, Issue 10, pp. 893-901, (2005) (PubMed).
Synonyme und alternative Namen zu RENT2/UPF2
UPF2, regulator of nonsense mediated mRNA decay (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), UPF2, regulator of nonsense mediated mRNA decay (Upf2), UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (upf2), HUPF2, RENT2, smg-3Bezeichner auf Proteinebene für RENT2/UPF2
- nonsense mRNA reducing factor 2
- regulator of nonsense transcripts 2
- smg-3 homolog, nonsense mediated mRNA decay factor
- up-frameshift suppressor 2 homolog
- yeast Upf2p homolog
- UPF2 regulator of nonsense transcripts homolog (yeast)
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