RAGE Proteine
(Advanced Glycosylation End Product-Specific Receptor (AGER))
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011].
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AGER
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
AGER
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
AGER
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 98 % as determined by reducing SDS-PAGE.
Active
AGER
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS, AcA
Active
AGER
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
AGER
Spezies: Human, Rind (Kuh), Affe, Panda
Wirt: Escherichia coli (E. coli)
Recombinant
WB, PC
Aktuelle Publikationen für unsere RAGE Proteine
: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." in: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).: "PD-L1 (Programmed Death Ligand 1) Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury." in: Stroke, Vol. 48, Issue 8, pp. 2255-2262, (2017) (PubMed).
: "A Novel, Multi-Target Natural Drug Candidate, Matrine, Improves Cognitive Deficits in Alzheimer's Disease Transgenic Mice by Inhibiting A? Aggregation and Blocking the RAGE/A? Axis." in: Molecular neurobiology, (2016) (PubMed).
: "The role of hyperglycemia in mechanisms of exacerbated inflammatory responses within the oral cavity." in: Cellular immunology, Vol. 272, Issue 1, pp. 45-52, (2011) (PubMed).
Aliase für RAGE Proteine
advanced glycosylation end-product specific receptor (AGER) Proteineadvanced glycosylation end product-specific receptor (Ager) Proteine
advanced glycosylation end-product specific receptor (Ager) Proteine
MAPK/MAK/MRK overlapping kinase (LOC719012) Proteine
AGER Proteine
RAGE Proteine
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