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RAF1 Proteine

(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].

13 Treffer

custom-made RAF1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7564914
 
custom-made RAF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7555117
 
RAF1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Pubmed 1 reference
Produktnummer ABIN7596475
 
RAF1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Produktnummer ABIN1317315
 
RAF1 Spezies: Human Wirt: Insektenzellen Recombinant 70 % - 90 % Func Active
Produktnummer ABIN5509125
 
RAF1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS
Produktnummer ABIN7579157
 
RAF1 Spezies: Hepatitis C Virus (HCV) Wirt: Escherichia coli (E. coli) Recombinant > 95 % pure ELISA, WB
Produktnummer ABIN2129667
 
RAF1 Spezies: Hepatitis C Virus (HCV) Wirt: Escherichia coli (E. coli) Recombinant > 95 % pure
Produktnummer ABIN935420
 
custom-made RAF1 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Produktnummer ABIN3136985
 
custom-made RAF1 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Produktnummer ABIN3094878
 
RAF1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5710215
 
RAF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2730424
 
RAF1 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7585818
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Standard (STD)
  • Reaktivität
    • Human
    • Hepatitis C Virus (HCV)
    • Mouse
    • Rat
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
    • Insect Cells
    • Yeast
  • Bindungsspezifität
    • AA 1-648
    • AA 1-130
    • AA 2061-2302
    • full length
  • Konjugat
    • GST tag
    • His tag
    • Strep Tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online
    • CUSABIO
    • OriGene
    • Signalway

Aktuelle Publikationen für unsere RAF1 Proteine

Rodríguez-Muñoz, de la Torre-Madrid, Sánchez-Blázquez, Garzón: "NO-released zinc supports the simultaneous binding of Raf-1 and PKC? cysteine-rich domains to HINT1 protein at the mu-opioid receptor." in: Antioxidants & redox signaling, Vol. 14, Issue 12, pp. 2413-25, (2011) (PubMed).

Aliase für RAF1 Proteine

Raf-1 proto-oncogene, serine/threonine kinase (RAF1) Proteine
Raf-1 proto-oncogene, serine/threonine kinase (Raf1) Proteine
Raf-1 proto-oncogene, serine/threonine kinase a (raf1a) Proteine
Raf-1 proto-oncogene, serine/threonine kinase (raf1) Proteine
v-raf-leukemia viral oncogene 1 (Raf1) Proteine
Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S) Proteine
6430402F14Rik Proteine
AA990557 Proteine
BB129353 Proteine
c-Raf Proteine
c-raf Proteine
CRAF Proteine
craf Proteine
cRaf Proteine
Craf1 Proteine
D830050J10Rik Proteine
NS5 Proteine
raf Proteine
Raf-1 Proteine
raf1 Proteine
RAF1 Proteine
v-Raf Proteine
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