IL-33 Protein

Produktnummer ABIN988078

IL-33-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für IL-33 Protein (ABIN988078)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % by SDS-PAGE and HPLC analyses.

Produktdetails

Sequenz: SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSK

Produktmerkmale: Fully biologically active when compared to standard. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106units/mg.

Endotoxin-Niveau: Level Less than 1EU/µg of rMuIL-33 as determined by LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at

Lagerung: 4 °C

Antigendetails

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Andere Bezeichnung: Interleukin-33 (IL-33)

Hintergrund: IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Synonym: Interleukin-33 (IL-33), Mouse. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, EDTA and DTT, pH 7.4.

Molekulargewicht: Approximately 17.5 kDa protein containing 158 amino acid residues.

Pathways: Production of Molecular Mediator of Immune Response