IFN alpha 1b (Active) Protein

Produktnummer ABIN987992

Dieses -Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für IFN alpha 1b (Active) Protein (ABIN987992)

Target: IFN alpha 1b

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 96 % by SDS-PAGE and HPLC analyses.

Produktdetails

Sequenz: MCDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMNVDSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM RSLSLSTNLQ ERLRRK

Produktmerkmale: Fully biologically active when compared to standard. The specific activity as determined in a viral resistance assay was found to be no less than 1.0 x 108 IU/mg.

Endotoxin-Niveau: Level Less than 1EU/µg of rHuIFNalpha1b as determined by LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Lagerung: 4 °C

Antigendetails

Target: IFN alpha 1b

Andere Bezeichnung: Interferon-Alpha1b (IFN-Alpha1b)

Hintergrund: At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end. Synonym: Interferon-alpha1b (IFN-alpha1b), Human. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, pH 7.4, containing 4% mannitol and 1% HSA.

Molekulargewicht: Approximately 19.5 kDa, a single non-glycosylated polypeptide chain containing 167 amino acids.