Complement C5b, 6 Complex (Active) Protein

Produktnummer ABIN935928

Produktdetails

Target: Complement C5b, 6 Complex

Biologische Aktivität: Active

Spezies: Human

Wirt: Bitte anfragen

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/ml

Buffer: Supplied as a frozen liquid with 10 mM HEPES and 120 mM NaCl, pH 7.2.
Biohazard Informations: This protein is purified from human plasma, therefore precautions appropriate for handling any blood-derived product must be use.

Lagerung: -80 °C

Antigendetails

Target: Complement C5b, 6 Complex

Hintergrund: Complement C5b, 6 complex, is a product of complement activation of  C5 and an intermediate in the formation of the C5b-9 membrane attack complex  (MAC) of complement. Each pathway of complement generates proteolytic enzyme complexes which are bound to the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing the highly potent anaphylatoxin C5a (74 amino acids) and activating C5b.This is the only proteolytic step in the assembly of the C5b-9 complex.
Description: Normal human serum. Synonyms: Anaphylatoxin C5b protein, C5 protein, Complement C5 protein, Complement C5b protein, Complement C5 precursor protein, Complement component 5 protein, CPAMD4 protein, C5b6 protein.