TIMP1 Protein
-
- Target Alle TIMP1 Proteine anzeigen
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Sequenz
- CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIA
- Produktmerkmale
-
Purified recombinant Human TIMP1 protein
Expression System: E.coli
Bioactivity: TIMP1 activity was measured by its ability to inhibit human MMP-1 induced hydrolysis of a chromogenic peptide substrate at room temperature. Half maximal inhibition was obtained at a TIMP-1 concentration of approximately 0.5 µg/mL, when using an MMP-1 concentration of 1.6 µg/mL. - Reinheit
- > 95 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product TIMP1 Protein
-
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) protein (Fc Tag)
TIMP1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-205) protein (Fc Tag)TIMP1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TIMP Metallopeptidase Inhibitor 1 (TIMP1) protein (His tag)TIMP1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >80 % as determined by reducing SDS-PAGE.
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) protein (GST tag)TIMP1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (Active) proteinTIMP1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (Active) proteinTIMP1 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
TIMP Metallopeptidase Inhibitor 1 (TIMP1) proteinTIMP1 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-205) protein (His tag)Crystallography grade TIMP1 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
-
- Target
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Andere Bezeichnung
- TIMP1 (TIMP1 Produkte)
- Synonyme
- TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
- Hintergrund
-
TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors.
Alternative Names: TIMP 1 protein, TIMP-1 protein, TIMP-1, Tissue inhibitor of metalloproteinases: Fibroblast collagenase inhibitor, Erythroid-potentiating activity protein, TIMP1, TIMP 1, TIMP-1 protein - Molekulargewicht
- 20.6 kDa
-
