Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TIMP1 Protein

Dieses Recombinant TIMP1-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN935874

Kurzübersicht für TIMP1 Protein (ABIN935874)

Target

Alle TIMP1 Proteine anzeigen
TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 12
  • 12
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Quelle

  • 19
  • 10
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % pure
  • Sequenz

    CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIA

    Produktmerkmale

    Purified recombinant Human TIMP1 protein
    Expression System: E.coli
    Bioactivity: TIMP1 activity was measured by its ability to inhibit human MMP-1 induced hydrolysis of a chromogenic peptide substrate at room temperature. Half maximal inhibition was obtained at a TIMP-1 concentration of approximately 0.5 µg/mL, when using an MMP-1 concentration of 1.6 µg/mL.

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
  • Möchten Sie weitere Optionen für dieses Protein ?

    !
    Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!

    Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen

  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

    Andere Bezeichnung

    TIMP1

    Hintergrund

    TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors.
    Alternative Names: TIMP 1 protein, TIMP-1 protein, TIMP-1, Tissue inhibitor of metalloproteinases: Fibroblast collagenase inhibitor, Erythroid-potentiating activity protein, TIMP1, TIMP 1, TIMP-1 protein

    Molekulargewicht

    20.6 kDa
Sie sind hier:
Chat with us!