Purified recombinant Human TIFF3 protein Expression System: E.coli Bioactivity: Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1.0-10.0 µg/mL.
Reinheit
> 98 % pure
Endotoxin-Niveau
< 0.1 ng per µg (1 EU/µg).
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
Supplied as a lyophilized powder.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
Target
TIFF3
Hintergrund
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation. Alternative Names: TIFF-3 protein, TIFF 3, Intestinal trefoil factor protein, TIFF-3, Trefoil Factor 3 protein, ITF protein, TIFF-3 protein, TFI protein, TIFF 3 protein, TIFF3