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Thymic Stromal Lymphopoietin Protein (TSLP)

Dieses Recombinant Thymic Stromal Lymphopoietin-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN935841

Kurzübersicht für Thymic Stromal Lymphopoietin Protein (TSLP) (ABIN935841)

Target

Alle Thymic Stromal Lymphopoietin (TSLP) Proteine anzeigen
Thymic Stromal Lymphopoietin (TSLP)

Protein-Typ

Recombinant

Spezies

  • 26
  • 10
  • 5
  • 3
Human

Quelle

  • 20
  • 15
  • 4
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

> 98 % pure
  • Sequenz

    MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKE MFAMKTKAAL AIWCPGYSET QINATQAMKK RRKRKVTTNK CLEQVSQLQG L WRRFNRPL LKQQ

    Produktmerkmale

    Purified recombinant Human TSLP protein
    Expression System: E.coli

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.

    Buffer

    Lyophilized from NaC2H3O2, pH 6.0.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    Thymic Stromal Lymphopoietin (TSLP)

    Andere Bezeichnung

    TSLP

    Hintergrund

    TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL7 and binds with the heterodimeric receptor complex consisting of the IL7R alpha chain (IL7Ra) and the TSLP-specific chain (TSLPR). Like IL7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs).
    Alternative Names: Thymic Stromal Lymphopoietin protein, TSLP protein

    Molekulargewicht

    15.0 kDa
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