Relaxin 3 Protein (RLN3)
Kurzübersicht für Relaxin 3 Protein (RLN3) (ABIN935768)
Target
Alle Relaxin 3 (RLN3) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Sequenz
- RAAPYGVRL CGREFIRAVI FTCGGSRW
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Produktmerkmale
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Purified recombinant Human Relaxin 3 protein
Expression System: E.coli -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Relaxin 3 (RLN3)
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Andere Bezeichnung
- Relaxin 3
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Hintergrund
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Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as "somatostatin-like" or "angiotensin-like" peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an "orphan" G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats.
Alternative Names: Relaxin-3 protein, Relaxin-3 protein, INSL7 protein, Relaxin-3, H3 relaxin protein, Insulin-like peptide-7 protein, Relaxin 3, Relaxin 3 protein, Relaxin 3 -
Molekulargewicht
- 5.5 kDa
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Pathways
- Hormone Activity, cAMP Metabolic Process
Target
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