Resistin Protein (RETN)
Kurzübersicht für Resistin Protein (RETN) (ABIN935761)
Target
Alle Resistin (RETN) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Sequenz
- SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS
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Produktmerkmale
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Purified recombinant Human Resistin protein
Expression System: E.coli -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 g/mL.
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Buffer
- Lyophilized from 20 mM tris, pH 8.0.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Resistin (RETN)
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Andere Bezeichnung
- Resistin
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Hintergrund
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Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes.
Alternative Names: Adipose tissue-specific secretory factor protein, FIZZ3 protein, ADSF protein -
Molekulargewicht
- 20.2 kDa
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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