Persephin Protein (PSPN)
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- Target Alle Persephin (PSPN) Proteine anzeigen
- Persephin (PSPN)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- ALAGSCRLWS LTLPVAELGL GYASEEKVIF RYCAGSCPQE ARTQHSLVLA RLRGRGRAHG RPCCQPTSYA DVTFLDDQHH WQQLPQLSAA ACGCGG
- Produktmerkmale
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Purified recombinant Human Persephin protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to stimulate proliferation of human thyroid carcinoma cells (TT cells) is 1 x 10^7 units/mg. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product PSPN Protein
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Persephin (PSPN) (AA 61-156) protein (His tag)
PSPN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Persephin (PSPN) (AA 22-156) protein (His tag)Crystallography grade PSPN Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Persephin (PSPN) (AA 22-156) protein (His tag)Crystallography grade PSPN Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- Persephin (PSPN)
- Andere Bezeichnung
- Persephin (PSPN Produkte)
- Synonyme
- PSPN Protein, PSP Protein, persephin Protein, PSPN Protein, Pspn Protein
- Hintergrund
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Persephin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Neurturin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Persephin signals through a multicomponent receptor system, composed of RET and one of four GFRa (a1-a4) receptors. The GFRa4 was first identified in chicken and was later shown to be the preferential binding subunit for Persephin. Persephin promotes the survival of ventral midbrain dompaminergic neurons and motor neurons after sciatic nerve oxotomy, and like GNDF, promotes ureteric bud branching. However, in contrast to GDNF and Neurturin, Persephin does not support survival of peripheral neurons.
Alternative Names: PSPN protein, PSP protein
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