NPX1 Protein

Produktnummer ABIN935691

Dieses Recombinant NPX1-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für NPX1 Protein (ABIN935691)

Target: NPX1 (Neuronal Pentraxin 1 (NPX1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: ACYCRIPACI AGERRYGYCI YQGRLWAFCC

Produktmerkmale: Purified recombinant Human NP1 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/mL.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: NPX1 (Neuronal Pentraxin 1 (NPX1))

Andere Bezeichnung: NP1

Hintergrund: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds.
Alternative Names: NP 1 protein, NP 1, Cryptdin protein, alpha Defensin-1 protein, Neutrophil Peptide-1 protein, HNP-1 protein, NP1, NP-1, NP-1 protein, NP-1 protein

Molekulargewicht: 3.4 kDa

Pathways: Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interaktom