CLCF1 Protein
Kurzübersicht für CLCF1 Protein (ABIN935688)
Target
Alle CLCF1 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF
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Produktmerkmale
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Purified recombinant Human NNT1 protein
Expression System: E.coli
Bioactivity: NT-1/BCSF-3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/mL. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (AA 29-225) protein (GST tag)
CLCF1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CLCF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cardiotrophin-Like Cytokine Factor 1 (CLCF1) proteinCLCF1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
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Andere Bezeichnung
- NNT1
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Hintergrund
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NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.
Alternative Names: NNT-1 protein, NNT-1 protein, Novel Neurtrophin-1/B-Cell Stimulating Factor-3 protein, Cardiotrophin-like cytokine protein, NNT 1, NNT 1 protein, NNT1, NNT-1 -
Molekulargewicht
- 22.4 kDa
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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