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ALOX5 Protein

ALOX5 Spezies: Human Wirt: Baculovirus Recombinant Active
Produktnummer ABIN935606
  • Target Alle ALOX5 Proteine anzeigen
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 5
    • 4
    • 3
    Human
    Quelle
    • 7
    • 2
    • 1
    • 1
    • 1
    Baculovirus
    Produktmerkmale
    Purified recombinant Human 5-Lipoxygenase protein
    Expression System: Baculovirus
    Bioactivity: 20 units/mg protein - One unit is defined as the amount of enzyme that consumes 1.0 nmol of oxygen per min at 25 °C in 50 mM Tris-HCl, 100 uM arachidonate, 2 mM CaCl2, 1 mM ATP, 250 uM oxygen. Oxygen consumption can be measured using a oxygraph equipped with a Clark oxygen electrode.
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  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    50 mM Tris containing 0 mM EDTA, pH 8.0.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -80 °C
  • Target
    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
    Andere Bezeichnung
    5-Lipoxygenase (ALOX5 Produkte)
    Synonyme
    5-LO Protein, 5-LOX Protein, 5LPG Protein, LOG5 Protein, 5LO Protein, 5LX Protein, AI850497 Protein, F730011J02 Protein, LOX5A Protein, si:dkey-194n13.2 Protein, lox5 Protein, arachidonate 5-lipoxygenase Protein, arachidonate 5-lipoxygenase a Protein, Arachidonate 5-lipoxygenase Protein, ALOX5 Protein, Alox5 Protein, alox5a Protein, AFUA_4G02770 Protein, AOR_1_1362014 Protein, lox5 Protein
    Hintergrund
    5-lipoxygenase (5-LO) catalyzes the formation of 5(S)-HpETE from arachidonic acid and its subsequent conversion to leukotriene A4. It is localized in the cytosol of resting human and rat peripheral blood neutrophils, whereas it is found in the nucleus in rat basophilic leukemia cells and human alveolar macrophages. Upon stimulation of the cell, 5-LO translocates to the nuclear membrane where it is found in association with 5-LO activating protein (FLAP) and with the 85 kDa cPLA2.
    Alternative Names: 5-Lipoxygenase Antigen, 5 Lipoxygenase Recombinant Protein
    Molekulargewicht
    78 kDa
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