ALOX5 Protein
Kurzübersicht für ALOX5 Protein (ABIN935606)
Target
Alle ALOX5 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
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                                            Produktmerkmale
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                        Purified recombinant Human 5-Lipoxygenase protein
 Expression System: Baculovirus
 Bioactivity: 20 units/mg protein - One unit is defined as the amount of enzyme that consumes 1.0 nmol of oxygen per min at 25 °C in 50 mM Tris-HCl, 100 uM arachidonate, 2 mM CaCl2, 1 mM ATP, 250 uM oxygen. Oxygen consumption can be measured using a oxygraph equipped with a Clark oxygen electrode.
 
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                                            Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Buffer
- 50 mM Tris containing 0 mM EDTA, pH 8.0.
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                                            Handhabung
- Avoid repeated freeze/thaw cycles.
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                                            Lagerung
- -80 °C
 
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    - ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
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                                            Andere Bezeichnung
- 5-Lipoxygenase
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                                            Hintergrund
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                        5-lipoxygenase (5-LO) catalyzes the formation of 5(S)-HpETE from arachidonic acid and its subsequent conversion to leukotriene A4. It is localized in the cytosol of resting human and rat peripheral blood neutrophils, whereas it is found in the nucleus in rat basophilic leukemia cells and human alveolar macrophages. Upon stimulation of the cell, 5-LO translocates to the nuclear membrane where it is found in association with 5-LO activating protein (FLAP) and with the 85 kDa cPLA2. 
 Alternative Names: 5-Lipoxygenase Antigen, 5 Lipoxygenase Recombinant Protein
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                                            Molekulargewicht
- 78 kDa
 Target
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