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ALOX5 Protein

Dieses Recombinant ALOX5-Protein wird in Baculovirus produziert.
Produktnummer ABIN935606

Kurzübersicht für ALOX5 Protein (ABIN935606)

Target

Alle ALOX5 Proteine anzeigen
ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 7
  • 4
  • 3
Human

Quelle

  • 7
  • 3
  • 2
  • 1
  • 1
Baculovirus
  • Produktmerkmale

    Purified recombinant Human 5-Lipoxygenase protein
    Expression System: Baculovirus
    Bioactivity: 20 units/mg protein - One unit is defined as the amount of enzyme that consumes 1.0 nmol of oxygen per min at 25 °C in 50 mM Tris-HCl, 100 uM arachidonate, 2 mM CaCl2, 1 mM ATP, 250 uM oxygen. Oxygen consumption can be measured using a oxygraph equipped with a Clark oxygen electrode.
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    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 12.620,45 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 20.480,57 €

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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    50 mM Tris containing 0 mM EDTA, pH 8.0.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -80 °C
  • Target

    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

    Andere Bezeichnung

    5-Lipoxygenase

    Hintergrund

    5-lipoxygenase (5-LO) catalyzes the formation of 5(S)-HpETE from arachidonic acid and its subsequent conversion to leukotriene A4. It is localized in the cytosol of resting human and rat peripheral blood neutrophils, whereas it is found in the nucleus in rat basophilic leukemia cells and human alveolar macrophages. Upon stimulation of the cell, 5-LO translocates to the nuclear membrane where it is found in association with 5-LO activating protein (FLAP) and with the 85 kDa cPLA2.
    Alternative Names: 5-Lipoxygenase Antigen, 5 Lipoxygenase Recombinant Protein

    Molekulargewicht

    78 kDa
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