IL-33 Protein
Kurzübersicht für IL-33 Protein (ABIN935587)
Target
Alle IL-33 (IL33) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI
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Produktmerkmale
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Purified recombinant Mouse IL33 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse D10S cells is ? 0.5 ng/mL, corresponding to a specific activity of ? 2 x 10^6units/mg. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- IL-33 (IL33) (Interleukin 33 (IL33))
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Andere Bezeichnung
- IL33
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Hintergrund
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IL33 is a proinflammatory protein that shares structural and functional characteristics with the IL1 cytokine family. It binds and signals through the IL1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL33 induces production of TH2 cell related cytokines, including IL4, IL5 and IL13, and exerts multiple inflammation related bioactivities.
Alternative Names: NF-HEV protein, IL-33 protein, IL 33 protein, IL-33, IL33, IL-33 protein, IL 33, Interleukin 33 protein -
Molekulargewicht
- 17.5 kDa
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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