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IGFBP7 Protein

Dieses Recombinant IGFBP7-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN935565

Kurzübersicht für IGFBP7 Protein (ABIN935565)

Target

Alle IGFBP7 Proteine anzeigen
IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Protein-Typ

Recombinant

Spezies

  • 14
  • 4
  • 2
  • 2
Human

Quelle

  • 11
  • 10
  • 1
Escherichia coli (E. coli)

Reinheit

> 98 % pure
  • Sequenz

    MSSSDTCGPC EPASCPPLPP LGCLLGETRD ACGCCPMCAR GEGEPCGGGG AGRGYCAPGM ECVKSRKRRK GKAGAAAGGP GVSGVCVCKS RYPVCGSDGT TYPSGCQLRA ASQRAESRGE KAITQVSKGT CEQGPSIVTP PKDIWNVTGA QVYLSCEVIG IPTPVLIWNK VKRGHYGVQR TELLPGDRDN LAIQTRGGPE KHEVTGWVLV SPLSKEDAGE YECHASNSQG QASASAKITV VDALHEIPVK KGEGAEL

    Produktmerkmale

    Purified recombinant Human IGF BP7 protein
    Expression System: E.coli

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C
  • Target

    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

    Andere Bezeichnung

    IGF BP7

    Hintergrund

    IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF1n a manner that inhibits IGF1nduced differentiation of skeletal myoblasts, without affecting IGF1nduced proliferation.
    Alternative Names: IGF binding protein related protein-1 protein, IGF BP 7, IGF BP-7, Mac25 protein, IGF BP-7 protein, IGF BP7, Insulin-like growth factor binding protein-7 protein, IGFBPrP1 protein, IGF BP 7 protein, IBP-7 protein, IGF BP-7 protein

    Molekulargewicht

    26.4 kDa

    Pathways

    Growth Factor Binding
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