IGFBP7 Protein
Kurzübersicht für IGFBP7 Protein (ABIN935565)
Target
Alle IGFBP7 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Sequenz
- MSSSDTCGPC EPASCPPLPP LGCLLGETRD ACGCCPMCAR GEGEPCGGGG AGRGYCAPGM ECVKSRKRRK GKAGAAAGGP GVSGVCVCKS RYPVCGSDGT TYPSGCQLRA ASQRAESRGE KAITQVSKGT CEQGPSIVTP PKDIWNVTGA QVYLSCEVIG IPTPVLIWNK VKRGHYGVQR TELLPGDRDN LAIQTRGGPE KHEVTGWVLV SPLSKEDAGE YECHASNSQG QASASAKITV VDALHEIPVK KGEGAEL
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Produktmerkmale
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Purified recombinant Human IGF BP7 protein
Expression System: E.coli -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
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Andere Bezeichnung
- IGF BP7
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Hintergrund
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF1n a manner that inhibits IGF1nduced differentiation of skeletal myoblasts, without affecting IGF1nduced proliferation.
Alternative Names: IGF binding protein related protein-1 protein, IGF BP 7, IGF BP-7, Mac25 protein, IGF BP-7 protein, IGF BP7, Insulin-like growth factor binding protein-7 protein, IGFBPrP1 protein, IGF BP 7 protein, IBP-7 protein, IGF BP-7 protein -
Molekulargewicht
- 26.4 kDa
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Pathways
- Growth Factor Binding
Target
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