IL-33 Protein

Produktnummer ABIN935563

Recombinant IL-33-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für IL-33 Protein (ABIN935563)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NESGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSET

Produktmerkmale: Purified recombinant Human IL33 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse D10S cells is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7units/mg.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Andere Bezeichnung: IL33

Hintergrund: Human IL31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
Alternative Names: IL 33 protein, IL-33, IL-33 protein, Interleukin 33 protein, IL-33 protein, NF-HEV protein, IL 33, IL33

Molekulargewicht: 15.8 kDa

Pathways: Production of Molecular Mediator of Immune Response