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IL-31 Protein

IL31 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935492
  • Target Alle IL-31 (IL31) Proteine anzeigen
    IL-31 (IL31) (Interleukin 31 (IL31))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 12
    • 5
    • 4
    • 2
    • 1
    Human
    Quelle
    • 12
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
    Produktmerkmale
    Purified recombinant Human IL31 protein
    Expression System: E.coli
    Bioactivity: Measured by its ability to induce STAT3 activation in human U87 cells.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL31 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with distilled water to a concentration of 0.1 - 0.5 mg/mL.
    Buffer
    Lyophilized from 10 mM Na3PO4, pH 7.5.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    IL-31 (IL31) (Interleukin 31 (IL31))
    Andere Bezeichnung
    IL31 (IL31 Produkte)
    Synonyme
    IL-31 Protein, 1700013B14Rik Protein, IL31 Protein, interleukin 31 Protein, IL31 Protein, Il31 Protein
    Hintergrund
    Human IL31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
    Alternative Names: Interleukin 31 protein, IL 31, IL 31 protein, IL31, IL-31, IL-31 protein, IL-31 protein
    Molekulargewicht
    15.8 kDa
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