IL-19 Protein

Produktnummer ABIN935484

Dieses Recombinant IL-19-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für IL-19 Protein (ABIN935484)

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA

Produktmerkmale: Purified recombinant Human IL19 protein
Expression System: E.coli
Bioactivity: Determined by its ability to activate STAT following receptor-ligand interaction.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 10 mM sodium citrate pH 3.0 to a concentration of 0.1-1.0 mg/mL.

Buffer: Lyophilized from 10 mM sodium citrate, pH 5.0.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Andere Bezeichnung: IL19

Hintergrund: IL19 belongs to the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL19 is a proinflammatory cytokine because it up-regulates IL6 and TNF-alpha and induces apoptosis through TNF-alpha. IL19 signals through the type I IL20R. Human and Mouse IL19 share 71 % amino acid sequence identity.
Alternative Names: IL-19, Melanoma differentiation association like protein protein, IL-19 protein, IL-19 protein, IL 19 protein, IL 19, IL19, Interleukin 19 protein

Molekulargewicht: 17.9 kDa