Purified recombinant Human GRO beta protein Expression System: E.coli Bioactivity: Determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/mL.
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant human GRO-beta is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. Alternative Names: MIP-2 protein, MGSA beta protein, Growth Regulated Protein/Melanoma Growth Stimulatory Activity protein, CXCL2 protein, GRO2 protein