GLP-1 Protein
Kurzübersicht für GLP-1 Protein (ABIN935397)
Target
Alle GLP-1 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Sequenz
- HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G
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Produktmerkmale
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Purified recombinant Human GLP1 protein
Expression System: E.coli -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- GLP-1 (Glucagon-like peptide 1 (GLP-1))
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Andere Bezeichnung
- GLP1
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Hintergrund
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GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic beta-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2.
Alternative Names: GLP 1 protein, GLP-1 protein, GLP 1, GLP-1, Glucagon-Like Peptide 1 protein, GLP1, GLP-1 protein -
Molekulargewicht
- 3.3 kDa
Target
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