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GLP-1 Protein

Dieses Recombinant GLP-1-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN935397

Kurzübersicht für GLP-1 Protein (ABIN935397)

Target

Alle GLP-1 Proteine anzeigen
GLP-1 (Glucagon-like peptide 1 (GLP-1))

Protein-Typ

Recombinant

Spezies

Human

Quelle

  • 3
Escherichia coli (E. coli)

Reinheit

> 98 % pure
  • Sequenz

    HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G

    Produktmerkmale

    Purified recombinant Human GLP1 protein
    Expression System: E.coli

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C
  • Target

    GLP-1 (Glucagon-like peptide 1 (GLP-1))

    Andere Bezeichnung

    GLP1

    Hintergrund

    GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic beta-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2.
    Alternative Names: GLP 1 protein, GLP-1 protein, GLP 1, GLP-1, Glucagon-Like Peptide 1 protein, GLP1, GLP-1 protein

    Molekulargewicht

    3.3 kDa
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