GDF5 Protein

Produktnummer ABIN935396

Dieses Recombinant GDF5-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für GDF5 Protein (ABIN935396)

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: APSATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR

Produktmerkmale: Purified recombinant Human GDF5 protein
Expression System: E.coli
Bioactivity: Induction of alkaline phosphatase activity in ATDC5 cells: EC50 = 40Nm.

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Testdurchführung:

Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 1.15 as the extinction coefficient for a 0.1 % (1 mg/mL) solution.
2. Analysis by RP-HPLC, using a standard solution of GDF5 as a Reference Standard.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: GDF5

Hintergrund: GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Alternative Names: BMP-14 protein, LAP4 protein, Growth Differentiation Factor 5 protein, GDF 5 protein, GDF-5 protein, Cartilage-derived morphogenetic protein-1 protein, GDF-5 protein, Radotermin protein, CDMP1 protein, GDF5 protein, GDF 5, BMP14 protein, Growth differentiation factor 5 protein, GDF-5 protein, CDMP-1 protein, SYNS2 protein, CDMP1 protein, GDF5, GDF-5

Molekulargewicht: 26.8 kDa