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GDF3 Protein

GDF3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935382
  • Target Alle GDF3 Proteine anzeigen
    GDF3 (Growth Differentiation Factor 3 (GDF3))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 2
    • 1
    • 1
    Human
    Quelle
    • 5
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequenz
    AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
    Produktmerkmale
    Purified recombinant Human GDF3 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/mL.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product GDF3 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
    Buffer
    Supplied lyophilized with no additives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    GDF3 (Growth Differentiation Factor 3 (GDF3))
    Andere Bezeichnung
    GDF3 (GDF3 Produkte)
    Synonyme
    KFS3 Protein, MCOP7 Protein, MCOPCB6 Protein, C78318 Protein, Gdf-3 Protein, Vgr-2 Protein, Vgr2 Protein, ecat9 Protein, RGD1564178 Protein, CVG1 Protein, der Protein, derriere Protein, gdf3-a Protein, vgr-2 Protein, vgr2 Protein, growth differentiation factor 3 Protein, growth differentiation factor 3 S homeolog Protein, GDF3 Protein, Gdf3 Protein, gdf3.S Protein
    Hintergrund
    GDF-3 is a member of the TGF beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.
    Alternative Names: GDF 3 protein, GDF-3 protein, GDF-3, GDF3, Growth/Differentiation Factor-3 protein, GDF-3 protein, GDF 3
    Molekulargewicht
    26 kDa
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