GDF3 Protein

Produktnummer ABIN935382

Produktdetails

Target: GDF3 (Growth Differentiation Factor 3 (GDF3))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG

Produktmerkmale: Purified recombinant Human GDF3 protein
Expression System: E.coli
Bioactivity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/mL.

Reinheit: > 98 % pure

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.

Buffer: Supplied lyophilized with no additives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Antigendetails

Target: GDF3 (Growth Differentiation Factor 3 (GDF3))

Andere Bezeichnung: GDF3 (GDF3 Produkte)

Hintergrund: GDF-3 is a member of the TGF beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.
Alternative Names: GDF 3 protein, GDF-3 protein, GDF-3, GDF3, Growth/Differentiation Factor-3 protein, GDF-3 protein, GDF 3

Molekulargewicht: 26 kDa