GDF11 Protein
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- Target Alle GDF11 Proteine anzeigen
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
- Produktmerkmale
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Purified recombinant Human GDF11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.08-0.10 µg/mL. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product GDF11 Protein
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Growth Differentiation Factor 11 (GDF11) (AA 310-407) protein (GST tag)
GDF11 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 11 (GDF11) (AA 299-407) protein (His tag)Crystallography grade GDF11 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Differentiation Factor 11 (GDF11) (AA 297-405) protein (His tag)Crystallography grade GDF11 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
- Buffer
- Supplied lyophilized with no additives.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Andere Bezeichnung
- GDF11 (GDF11 Produkte)
- Synonyme
- BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein
- Hintergrund
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GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90 % identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same.
Alternative Names: BMP-11 protein, GDF 11 protein, GDF-11 protein, GDF-11 protein, GDF-11, Growth/Differentiation Factor-11 protein, GDF11, GDF 11 - Molekulargewicht
- 25 kDa
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