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CYR61 Protein

This anti-CYR61 antibody (ABIN935294) is a Escherichia coli (E. coli) antibody detecting CYR61 in . Suitable for Human.
Produktnummer ABIN935294

Kurzübersicht für CYR61 Protein (ABIN935294)

Target

Alle CYR61 Proteine anzeigen
CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 7
  • 3
  • 1
  • 1
  • 1
Human

Quelle

  • 4
  • 4
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Reinheit

> 95 % pure
  • Sequenz

    MTCPAACHCP LEAPKCAPGV GLVRDGCGCC KVCAKQLNED CSKTQPCDHT KGLECNFGAS STALKGICRA QSEGRPCEYN SRIYQNGESF QPNCKHQCTC IDGAVGCIPL CPQELSLPNL GCPNPRLVKV TGQCCEEWVC DEDSIKDPME DQDGLLGKEL GFDASEVELT RNNELIAVGK GSSLKRLPVF GMEPRILYNP LQGQKCIVQT TSWSQCSKTC GTGISTRVTN DNPECRLVKE TRICEVRPCG QPVYSSLKKG KKCSKTKKSP EPVRFTYAGC LSVKKYRPKY CGSCVDGRCC TPQLTRTVKM RFRCEDGETF SKNVMMIQSC KCNYNCPHAN EAAFPFYRLF NDIHKFRD

    Produktmerkmale

    Purified recombinant Human CYR61 protein
    Expression System: E.coli
    Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Mouse 3T3 cells. The expected ED50 for this effect is 2.0-3.0 µg/mL.

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

    Andere Bezeichnung

    CYR61

    Hintergrund

    CYR61 is a member of the CCN family of secreted cysteine rich regulatory proteins. CYR61 induces angiogenesis by stimulating the proliferation, migration, and adhesion of endothelial cells. Cell migration and adhesion are mediated through binding to specific cell surface integrins and to heparin sulfate proteoglycans. Increased expression of CYR61 is associated with several types of cancer, and correlates with the progression and estrogen independence of human breast cancers. Recombinant human CYR61 is a 39.5 kDa protein containing 357 amino acid residues. It is composed of four distinct structural domains (modules), the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the Thrombospondin type-I (TSP type-1) domain, and a C-terminal cysteine knot-like domain (CTCK).
    Alternative Names: CYR61, CYR6-1 protein, CYR-61 protein, CYR 61, CYR 61 protein, CYR-61, CCN1 protein, GIGI protein protein

    Pathways

    Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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