Defensin beta 4 Protein (DEFB4) (AA 33-47)
Kurzübersicht für Defensin beta 4 Protein (DEFB4) (AA 33-47) (ABIN935250)
Target
Alle Defensin beta 4 (DEFB4) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 33-47
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Sequenz
- EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
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Produktmerkmale
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Purified recombinant Human BD4 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/mL. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Defensin beta 4 (DEFB4)
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Andere Bezeichnung
- BD4
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Hintergrund
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney.
Alternative Names: BEFB4 protein, BD 4 protein, beta-defensin 104 protein, BD 4 protein, BD-4, BD-4 protein, BD 4, BD4, BD-4 protein -
Molekulargewicht
- 6.0 kDa
Target
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