BMP7 Protein
Kurzübersicht für BMP7 Protein (ABIN935247)
Target
Alle BMP7 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH
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Produktmerkmale
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Purified recombinant Human BMP7 protein
Expression System: CHO cells
Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.02-0.04 µg/mL. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Bone Morphogenetic Protein 7 (BMP7) (AA 1-431) protein (GST tag)
BMP7 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 7 (BMP7) (AA 292-430) (Active) protein (His tag)BMP7 Spezies: Maus Wirt: Escherichia coli (E. coli) > 97 % AcA, CC Active
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
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Andere Bezeichnung
- BMP7
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Hintergrund
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BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures.
Alternative Names: BMP 7 protein, BMP7, Bone Morphogenetic protein 7 protein, BMP-7, BMP-7 protein, OP-1 protein, BMP 7, BMP-7 protein -
Molekulargewicht
- 28.8 kDa
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Pathways
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
Target
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