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BMP6 Protein

BMP6 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % pure Active
Produktnummer ABIN935246
  • Target Alle BMP6 Proteine anzeigen
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 7
    • 4
    • 2
    Human
    Quelle
    • 6
    • 4
    • 2
    • 1
    HEK-293 Cells
    Sequenz
    VSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNAT NHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH
    Produktmerkmale
    Purified recombinant Human BMP6 protein
    Expression System: HEK cells
    Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 µg/mL.
    Reinheit
    > 95 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product BMP6 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 10 mM Tris, pH 9.0.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Andere Bezeichnung
    BMP6 (BMP6 Produkte)
    Synonyme
    BMP6 Protein, zgc:113595 Protein, vgr Protein, vgr-1 Protein, vgr1 Protein, VGR Protein, VGR1 Protein, D13Wsu115e Protein, Vgr1 Protein, bone morphogenetic protein 6 Protein, bone morphogenetic protein 6 S homeolog Protein, BMP6 Protein, bmp6 Protein, bmp6.S Protein, Bmp6 Protein
    Hintergrund
    TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown.
    Alternative Names: BMP 6 protein, VGR protein, BMP6, Bone Morphogenetic protein 6 protein, BMP-6, BMP-6 protein, BMP-6 protein, BMP 6
    Molekulargewicht
    26.2 kDa
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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