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BMP6 Protein

Dieses Recombinant BMP6-Protein wird in HEK-293 Cells produziert.
Produktnummer ABIN935246

Kurzübersicht für BMP6 Protein (ABIN935246)

Target

Alle BMP6 Proteine anzeigen
BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 7
  • 3
  • 2
Human

Quelle

  • 8
  • 4
HEK-293 Cells

Reinheit

> 95 % pure
  • Sequenz

    VSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNAT NHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH

    Produktmerkmale

    Purified recombinant Human BMP6 protein
    Expression System: HEK cells
    Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 µg/mL.

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

    Buffer

    Lyophilized from 10 mM Tris, pH 9.0.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    BMP6 (Bone Morphogenetic Protein 6 (BMP6))

    Andere Bezeichnung

    BMP6

    Hintergrund

    TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown.
    Alternative Names: BMP 6 protein, VGR protein, BMP6, Bone Morphogenetic protein 6 protein, BMP-6, BMP-6 protein, BMP-6 protein, BMP 6

    Molekulargewicht

    26.2 kDa

    Pathways

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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