GDF6 Protein

Produktnummer ABIN935239

Recombinant GDF6-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für GDF6 Protein (ABIN935239)

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % pure

Produktdetails

Sequenz: TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR

Produktmerkmale: Purified recombinant Human BMP13 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/mL.

Endotoxin-Niveau: < 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Kommentare:

Biological activity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

Buffer: Supplied lyophilized with no additives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Andere Bezeichnung: BMP13

Hintergrund: BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains.
Alternative Names: BMP-13 protein, BMP-13, BMP 13, CDMP-2 protein, BMP-13 protein, Cartilage-Derived Morphogenetic Protein-2 protein, Bone Morphogenetic protein 13 protein, BMP13, GDF-6 protein, BMP 13 protein

Molekulargewicht: 27.5 kDa