GDF6 Protein
Kurzübersicht für GDF6 Protein (ABIN935239)
Target
Alle GDF6 Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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                                            Sequenz
- TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
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                                            Produktmerkmale
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                        Purified recombinant Human BMP13 protein
 Expression System: E.coli
 Bioactivity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/mL.
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                                            Endotoxin-Niveau
- < 0.1 ng per μg (1 EU/μg).
 
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                                            Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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                                            Kommentare
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                        Biological activity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 μg/mL. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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                                            Buffer
- Supplied lyophilized with no additives.
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                                            Konservierungsmittel
- Without preservative
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                                            Handhabung
- Avoid repeated freeze/thaw cycles.
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                                            Lagerung
- 4 °C/-20 °C
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                                            Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
 
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    - GDF6 (Growth Differentiation Factor 6 (GDF6))
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                                            Andere Bezeichnung
- BMP13
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                                            Hintergrund
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                        BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. 
 Alternative Names: BMP-13 protein, BMP-13, BMP 13, CDMP-2 protein, BMP-13 protein, Cartilage-Derived Morphogenetic Protein-2 protein, Bone Morphogenetic protein 13 protein, BMP13, GDF-6 protein, BMP 13 protein
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                                            Molekulargewicht
- 27.5 kDa
 Target
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