Defensin beta 3 Protein (DEFB3)
Kurzübersicht für Defensin beta 3 Protein (DEFB3) (ABIN935229)
Target
Alle Defensin beta 3 (DEFB3) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
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Produktmerkmale
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Purified recombinant Human BD3 protein
Expression System: E.coli
Bioactivity: Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli. -
Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Supplied lyophilized with no additives.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Defensin beta 3 (DEFB3)
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Andere Bezeichnung
- BD3
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Hintergrund
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
Alternative Names: BD-3 protein, BD 3, BD 3 protein, BD3, BD-3 protein, beta-defensin-3 protein, BD 3 protein, BD-3 -
Molekulargewicht
- 3.9 kDa
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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