ARTN Protein
Kurzübersicht für ARTN Protein (ABIN935222)
Target
Alle ARTN Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG
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Produktmerkmale
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Purified recombinant Human Artemin protein
Expression System: E.coli
Bioactivity: Determined by it's ability to promote survival and neurite outgrowth and dorsal root ganglion neurons. -
Aufreinigung
- Heat shock method
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Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
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Artemin (ARTN) (AA 112-224) protein (Fc Tag)
ARTN Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Artemin (ARTN) (AA 108-220) protein (His-IF2DI Tag)ARTN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Artemin (ARTN) (AA 108-220) protein (Fc Tag)ARTN Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Artemin (ARTN) (AA 1-228) protein (GST tag)ARTN Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Artemin (ARTN) proteinARTN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 98,00% SDS
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- ARTN (Artemin (ARTN))
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Andere Bezeichnung
- Artemin
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Hintergrund
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Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRalpha (alpha1-alpha4) receptors. Artemin prefers the receptor GFRalpha3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons.
Alternative Names: EVN protein, Enovin protein, ART protein, Neublastin protein , ARTN protein, NBN protein -
Molekulargewicht
- 24.4 kDa
Target
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