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Globular Acrp30 (Adipolean) (Active) Protein

Recombinant -Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN935218

Kurzübersicht für Globular Acrp30 (Adipolean) (Active) Protein (ABIN935218)

Target

Globular Acrp30 (Adipolean)

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 1
  • 1
Human

Quelle

  • 2
Escherichia coli (E. coli)

Reinheit

> 98 % pure
  • Sequenz

    PGAEGPRGFP GIQGRKGEPG EGAYVYRSAF SVGLETYVTI PNMPIRFTKI FYNQQNHYDG STGKFHCNIP GLYYFAYHIT VYMKDVKVSL FKKDKAMLFT YDQYQENNVD QASGSVLLHL EVGDQVWLQV YGEGERNGLY ADNDNDSTFT GFLLYHDTN

    Produktmerkmale

    Purified recombinant Human gAcrp30 protein
    Expression System: E.coli
    Bioactivity: Determined by a cytotoxicity assay using M1 cells. The expected ED50 for this effect is 0.5-1.0 µg/mL.

    Endotoxin-Niveau

    < 0.1 ng per µg (1 EU/µg).
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    Globular Acrp30 (Adipolean)

    Hintergrund

    The gAcrp30 variant is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05 % of total serum protein. Like Adiponectin, Acrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver.
    Alternative Names: Adiponectin protein, gAcrp 30, gAcrp-30 protein, gAcrp-30 protein, gAcrp-30, apm-1 variant protein, gAcrp 30 protein, gAcrp30

    Molekulargewicht

    18.1 kDa
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