CAPG Protein (AA 1-348)

Produktnummer ABIN935076

Produktdetails

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-348

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Sequenz: MYTAIPQSGS PFPGSVQDPG LHVWRVEKLK PVPVAQENQG VFFSGDSYLV LHNGPEEVSH LHLWIGQQSS RDEQGACAVL AVHLNTLLGE RPVQHREVQG NESDLFMSYF PRGLKYQEGG VESAFHKTST GAPAAIKKLY QVKGKKNIRA TERALNWDSF NTGDCFILDL GQNIFAWCGG KSNILERNKA RDLALAIRDS ERQGKAQVEI VTDGEEPAEM IQVLGPKPAL KEGNPEEDLT ADKANAQAAA LYKVSDATGQ MNLTKVADSS PFALELLISD DCFVLDNGLC GKIYIWKGRK ANEKERQAAL QVAEGFISRM QYAPNTQVEI LPQGRESPIF KQFFKDWK

Produktmerkmale: Purified recombinant Human CAPG protein
Expression System: E.coli

Reinheit: > 95 % pure

Anwendungsinformationen

Applikationshinweise: CAPG protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, and 10 % glycerol.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Andere Bezeichnung: CAPG (CAPG Produkte)

Synonyme: AFCP Protein, MCP Protein, gCap39 Protein, mbh1 Protein, capping actin protein, gelsolin like Protein, capping protein (actin filament), gelsolin-like Protein, CAPG Protein, Capg Protein

Hintergrund: Macrophage-capping protein, also known as CAPG, belongs to the gelsolin/villin family of actin-regulatory proteins. CAPG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. This protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. Recombinant human CAPG was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Capping protein gelsolin like protein, Myc basic motif homolog 1., Actin regulatory protein CAP G protein, gCap39 protein, MCP protein, CAPG protein, Macrophage capping protein protein, mbh1 protein, Gelsolin like capping protein protein, AFCP protein, Macrophage-capping protein Actin capping protein GCAP39 protein, Capping protein (actin filament) gelsolin like protein

Molekulargewicht: 38.5 kDa (348 AA)

Pathways: Regulation of Actin Filament Polymerization