Alcohol Dehydrogenase (ADH) (AA 1-325) Protein

Produktnummer ABIN935073

Dieses Recombinant -Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für Alcohol Dehydrogenase (ADH) (AA 1-325) Protein (ABIN935073)

Target: Alcohol Dehydrogenase (ADH)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 % pure

Produktdetails

Proteineigenschaft: AA 1-325

Sequenz: MAASCVLLHT GQKMPLIGLG TWKSEPGQVK AAVKYALSVG YRHIDCAAIY GNEPEIGEAL KEDVGPGKAV PREELFVTSK LWNTKHHPED VEPALRKTLA DLQLEYLDLY LMHWPYAFER GDNPFPKNAD GTICYDSTHY KETWKALEAL VAKGLVQALG LSNFNSRQID DILSVASVRP AVLQVECHPY LAQNELIAHC QARGLEVTAY SPLGSSDRAW RDPDEPVLLE EPVVLALAEK YGRSPAQILL RWQVQRKVIC IPKSITPSRI LQNIKVFDFT FSPEEMKQLN ALNKNWRYIV PMLTVDGKRV PRDAGHPLYP FNDPY

Produktmerkmale: Purified recombinant Human Alcohol dehydrogenase protein
Expression System: E.coli

Anwendungsinformationen

Applikationshinweise: Alcohol dehydrogenase protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 50 mM NaCl and 10 % glycerol.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: Alcohol Dehydrogenase (ADH)

Andere Bezeichnung: Alcohol dehydrogenase

Hintergrund: Alcohol dehydrogenase [NADP+] (AKR1A1) is a member of the aldo/keto reductase superfamily and catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. This protein is closely related (65 % identity) to aldose reductase, an enzyme involved in the pathogenesis of some diabetic and galactosemic complications. It plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Recombinant human Alcohol dehydrogenase was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: ALDR1 protein, Alcohol dehydrogenase [NADP+] Alcohol dehydrogenase protein, Aldehyde reductase protein, AKR1A1 protein, ARM protein, aldo-keto reductase family 1 member A1 (aldehyde reductase)., ALR protein, DD3 protein

Molekulargewicht: 36.5 kDa (325 AA)