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Troponin C (AA 1-160) Protein

Recombinant -Protein exprimiert in Escherichia coli (E. coli).
Produktnummer ABIN935041

Kurzübersicht für Troponin C (AA 1-160) Protein (ABIN935041)

Target

Troponin C

Protein-Typ

Recombinant

Spezies

  • 1
  • 1
  • 1
Human

Quelle

  • 2
  • 1
Escherichia coli (E. coli)

Applikation

SDS-PAGE (SDS)

Reinheit

> 95 % pure
  • Proteineigenschaft

    AA 1-160

    Sequenz

    MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ

    Produktmerkmale

    Purified recombinant Human Troponin C protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
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  • Applikationshinweise

    Troponin C protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 0 mM DTT, 100 mM NaCl, and 10 % glycerol.

    Konservierungsmittel

    Dithiothreitol (DTT)

    Vorsichtsmaßnahmen

    This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C

    Informationen zur Lagerung

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target

    Troponin C

    Hintergrund

    Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I(Tn-1), Troponin T(Tn-T) and Troponin C(Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Recombinant human Troponin C was expressed in E. coli and purified by using conventional chromatography.
    Alternative Names: Troponin C protein, , Fast skeletal muscle troponin C protein, skeletal muscle protein, Troponin C protein, TNNC2 protein, Troponin C protein, Troponin C type 1 (slow) protein, skeletal muscle TNNC1 protein, Cardiac troponin C protein, Skeletal troponin C protein, slow skeletal and cardiac muscles protein, TNNC protein, Troponin C1 slow protein, Troponin C type 2 (fast) protein

    Molekulargewicht

    18.1 kDa (160 AA)
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