Factor VII Protein

Produktnummer ABIN934812

Dieses Native Factor VII-Protein wird in Human exprimiert.

Kurzübersicht für Factor VII Protein (ABIN934812)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Protein-Typ: Native

Biologische Aktivität: Active

Spezies: Human

Quelle: Human

Reinheit: > 95 % pure

Produktdetails

Produktmerkmale: Purified native Human Factor VII protein
Bioactivity: 3296 units/mg protein - Specific activity is determined by the Factor VII clotting assay. One unit of activity is equivalent to the factor VII activity in one milliliter of normal plasma.
Protein Source: Human serum/plasma

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 % Glycerol/H2 O (vol/vol).

Vorsichtsmaßnahmen: Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Antigendetails

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Andere Bezeichnung: Factor VII

Hintergrund: Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa.
Description: Human serum/plasma.
Alternative Names: Complement Factor VII

Molekulargewicht: 50 kDa

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling