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Factor VII Protein

Dieses Native Factor VII-Protein wird in Human exprimiert.
Produktnummer ABIN934812

Kurzübersicht für Factor VII Protein (ABIN934812)

Target

Alle Factor VII (F7) Proteine anzeigen
Factor VII (F7) (Coagulation Factor VII (F7))

Protein-Typ

Native

Biologische Aktivität

Active

Spezies

  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Quelle

  • 12
  • 5
  • 3
  • 1
  • 1
Human

Reinheit

> 95 % pure
  • Produktmerkmale

    Purified native Human Factor VII protein
    Bioactivity: 3296 units/mg protein - Specific activity is determined by the Factor VII clotting assay. One unit of activity is equivalent to the factor VII activity in one milliliter of normal plasma.
    Protein Source: Human serum/plasma
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  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    50 % Glycerol/H2 O (vol/vol).

    Vorsichtsmaßnahmen

    Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot and store at -20 °C.
  • Target

    Factor VII (F7) (Coagulation Factor VII (F7))

    Andere Bezeichnung

    Factor VII

    Hintergrund

    Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa.
    Description: Human serum/plasma.
    Alternative Names: Complement Factor VII

    Molekulargewicht

    50 kDa

    Pathways

    Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
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