IL16 Protein

Produktnummer ABIN934622

Dieses Recombinant IL16-Protein wird in Escherichia coli (E. coli) produziert. Es ist 1 Publikation verfügbar.

Kurzübersicht für IL16 Protein (ABIN934622)

Target: IL16 (Interleukin 16 (IL16))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 97 % pure

Produktdetails

Sequenz: MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS

Produktmerkmale: Purified recombinant Human IL16 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human CD4+ T lymphoytes using a concentration range of 1.0-100.0 ng/mL.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL.

Buffer: Lyophilized from 5 mM Na3PO4, pH 7.6.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Referenzen

Liu, Mills, Dixon, Vennarini, Cunningham, Del Vecchio, Das, Glass: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).

Antigendetails

Target: IL16 (Interleukin 16 (IL16))

Andere Bezeichnung: IL16

Hintergrund: IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
Alternative Names: IL-16 protein, IL16, IL-16 protein, Interleukin 16 protein, IL 16, Lymphocyte Chemoattractant Factor protein, IL 16 protein, LCF protein, IL-16

Molekulargewicht: 13.5 kDa